Naloxone

An opioid overdose happens when the drugs slow down or stop a person’s breathing. This is because opioids attach to certain parts of the brain that control breathing. Naloxone  works by attaching to those same parts of the brain and blocking the opioids. This helps the person start breathing normally again.

Watch a video about how Naloxone works.

Naloxone does not affect someone who isn’t having an opioid overdose. It’s also been shown to be safe for people who may have used other types of drugs.

There are two main types of naloxone: a nasal spray and a shot. The nasal spray is easier to use and more common. The shot works faster, but it needs more skill and preparation to use.

Naloxone acts quickly and is very effective, but it only lasts for 30 to 90 minutes. That means the overdose can return after that time. It’s important to stay with the person and call for emergency help. If the person shows signs of overdose again, give another dose. 

Naloxone will have no side effects for many people. People who use opioids often and are physically dependent may have withdrawal symptoms after receiving naloxone. These symptoms can include headaches, sweating, feeling sick to the stomach, vomiting, shaking, fast heartbeat, and changes in blood pressure. Some people may wake up feeling confused, angry, or upset because of these effects.