Opioids are a type of drug that can come from different sources. Some are made from a plant called the opium poppy, while others are made partly or completely in a lab (synthetic or semi-synthetic). They include prescription pain medicines and illegal drugs.
Doctors sometimes prescribe opioids to help people manage pain from an injury, illness, or surgery. They can come as pills, skin patches, or shots.
All opioids can be addictive, even when prescribed by a doctor. When someone uses opioids for a long time, their body can get used to the drug. This means they may need to take more to feel the same effect (tolerance), which can be dangerous and lead to overdose.
When a person takes an opioid, it goes into their bloodstream and travels through the body to the brain. There, it connects to special spots called opioid receptors. These receptors cause the brain to release chemicals called endorphins, which causes pleasure and reduces pain.

Opioid Use Disorder, or OUD, is a health condition that happens when someone has trouble controlling their use of opioids. Even though some opioids are prescribed by a doctor, using them too much - or using illegal opioids - can lead to this disorder.
Common signs of OUD include:
OUD is a serious but treatable condition. There are many ways to get help and start recovery.
An overdose happens when someone takes too much of an opioid, and the drug overwhelms the body. Opioids affect the part of the brain that controls breathing. When too much is taken, breathing can slow down or stop. This can cause the brain to lose oxygen, which may lead to brain damage or even death.
Common signs of an overdose include:
If you think someone is having an overdose, call 911 right away. If you have Naloxone (Narcan), give it to them as soon as possible. Try to keep the person breathing by giving rescue breaths or CPR until help arrives.

More people are dying from opioid overdoses, and a big reason is synthetic opioids like fentanyl. Fentanyl is much stronger than most other opioids and is often mixed into street drugs without people knowing. It’s becoming more common in Sacramento.
Fentanyl is a man-made drug used to treat severe pain. It is about 100 times stronger than morphine and 50 times stronger than heroin.
Like other opioids, it can make people feel:
Fentanyl can be taken in many ways — as a pill, by snorting or smoking it, by injection, on blotter paper, or in a patch. It is often hidden in other street drugs, and you can’t tell if something has fentanyl in it by looking, tasting, smelling, or touching it.
No. Directly touching or being around fentanyl will not lead to an overdose.
It must be introduced into the bloodstream or a mucus membrane in order for it to work (i.e. enter into the body).
Fentanyl on your skin takes about 48 to 72 hours to absorb if not cleaned off, unless it goes through an open wound.
Even though touching fentanyl won't lead to an overdose, avoid direct contact with any suspicious substances.
Fentanyl in powdered form needs to be disturbed in order to get into the air and potentially be inhaled. If you're unable to distance yourself or are worried about disturbing it, use a wet cloth/paper towel to cover it.
If you accidentally touch fentanyl, wash your hands as soon as you can with soap and water, and avoid touching your face. Avoid using hot water and alcoholic hand sanitizers and soaps, as that can increase absorption into the skin.
If you believe you or someone got fentanyl into their system, monitor for symptoms of fentanyl use and overdose and administer Naloxone if necessary.
Fentanyl test strips are small strips of paper that can detect the presence of fentanyl in different drugs and drug forms. Test strips provide important information about fentanyl in the illegal drug supply so communities and people who use drugs can take steps to reduce risk of overdose.
The DEA has reported that over 6 in 10 illicit pills are laced with fentanyl. It's commonly found in other drugs such as heroin, cocaine, methamphetamine, ketamine, and pills from non-medical sources.
Fentanyl can only be detected through test strips, and is impossible to be detected by sight, smell, or taste. Knowing if the drugs you plan to use contain fentanyl can lower your risk of overdose.

Naloxone, also known as Narcan, is a medication which can save someone's life from an opioid overdose.
Naloxone is an opioid antagonist designed to rapidly reverse the effects of an opioid overdose. The Coalition offers free trainings and free kits upon request.
An opioid overdose happens when the drugs slow down or stop a person’s breathing. This is because opioids attach to certain parts of the brain that control breathing. Naloxone works by attaching to those same parts of the brain and blocking the opioids. This helps the person start breathing normally again.
Watch a video about how Naloxone works.
Naloxone does not affect someone who isn’t having an opioid overdose. It’s also been shown to be safe for people who may have used other types of drugs.
There are two main types of naloxone: a nasal spray and a shot. The nasal spray is easier to use and more common. The shot works faster, but it needs more skill and preparation to use.
Naloxone acts quickly and is very effective, but it only lasts for 30 to 90 minutes. That means the overdose can return after that time. It’s important to stay with the person and call for emergency help. If the person shows signs of overdose again, give another dose.
Naloxone will have no side effects for many people. People who use opioids often and are physically dependent may have withdrawal symptoms after receiving naloxone. These symptoms can include headaches, sweating, feeling sick to the stomach, vomiting, shaking, fast heartbeat, and changes in blood pressure. Some people may wake up and seem confused, angry, or upset because of these effects.
It is important to space naloxone doses out by 2-3 minutes, with rescue breathing in-between doses. This helps reduce the risk of precipitated withdrawal and gives the naloxone a few minutes to work.
Note: Narcan is a common brand name for the medication naloxone - they work the same way. Both save lives!
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